Similar disorders
Hepatosplenomegaly (HSM) is a medical condition that includes swelling and enlargement of both the liver and spleen. HSM is similar to a great extent to splenomegaly in causes, symptoms, and investigations but it is often more serious.
Many people may get confused between splenomegaly and hypersplenism. Hypersplenism is a functional disorder of the spleen in which the spleen is overactive and functioning more than normal regardless of its size while splenomegaly’s main criterion is spleen enlargement.