Ulcerative Colitis (UC): Causes, Symptoms, Types, Diagnosis & Treatment

2) Pathology

Crohn’s disease shows granuloma on biopsy and severe stricture on endoscopy.

Ulcerative colitis shows crypts abscesses on biopsy, but there is no stricture or granulomas.

Also, biopsies show a transmural lesion in Crohn’s disease. But, they show only mucosal and submucosal affection in ulcerative colitis.