What is hemophilia?
Hemophilia is a genetic disorder that diminishes the body’s ability to make blood clots that are needed to stop bleeding. In hemophilic patients, bleeding continues for a long time after an injury, easy bruising, and an enhanced risk of bleeding within joints or the brain. Mild cases of the condition may have symptoms only after an accident or during surgery.
Bleeding into a joint may result in permanent damage while in the brain may end up in long term headaches, seizures, or lack of awareness.
How does bleeding start and stop?
- Bleeding begins when a capillary is hurt, and blood flows out.
- The capillary contracts to reduce the bleeding.
- Then platelets make a plug to patch the crack.
- Next, numerous clotting factors in plasma cooperate to build up a clot that makes the plug more effective and stops the bleeding.
How does hemophilia affect the blood?
Platelets are essential for blood clotting as they have an adhesive surface that allows them to tramp together to stop the leak of blood.
Clotting factors are proteins that form a “network” around the platelets, supporting them to stay in position.
There are various clotting factors in the blood that enumerated using Roman numbers.
A child with hemophilia A does not have sufficient clotting factor VIII (8) in their blood. A child with hemophilia B does not have adequate clotting factor IX (9) in their blood.
In hemophilia, the missing clotting factor makes it hard to build a clot. Your bleeding will remain longer than usual.
⇒ Now, let’s discuss types of hemophilia.